Details of project
Sl no | Item | Details |
1 | Project title | “Effect of Yoga and Meditation on Hippocampal Volumetry and Memory Among People with Chronic Drug Resistant Mesial Temporal Sclerosis: A Comparative Study Before and After Epilepsy Surgery” |
2 | List of investigators | · Principal Investigator:
· Dr Bhaskara Rao Malla · Co-Investigators · Dr Arivazhagan A · Dr Jamuna Rajeswaran · Dr Rita Christopher · Dr Sathyaprabha · Dr Venkatasubramanian G · Dr Shivarama Varambally · Dr Satishchandra P · Dr Sanjib Sinha · Dr Jitender Saini · Dr K Thennarasu |
3 | Funding Agency | DST-SATYAM, New Delhi
(Project Code: DST/003/306/2016/00920) |
4 | Date of commencement | 29-10-2016 |
5 | Date of Completion | 28-10-2019 (No cost extension up to April 2020) |
6 | Inclusion/ Exclusion criteria | Inclusion:
1) Age bracket: 18-50 Years 2) Gender: Both Male & Female 3) People with Chronic Drug Resistant (DRE) Mesial Temporal Lobe Epilepsy (MTLE) 4) A radiological diagnosis of Mesial Temporal Sclerosis (MTS) 5) Willing for surgery and the study
Exclusion: 1) Drug resistant neo-cortical, temporal plus or extra temporal lobe epilepsy 2) No MTS on MRI or having neoplastic and vascular lesions 3) Not willing for the surgery/ study 4) Previously operated case |
7 | Sample size | N=60 (Y=30, C=30) |
8 | Intervention/s | Yoga for Epilepsy Module |
9 | Timeline | Recruitment-Baseline assessments (1st time point)-12 days Yoga sessions under supervision &3 months Yoga practice at home (Video assisted)-2nd time point assessments (before surgery)-Surgery-6 days Booster Yoga sessions under supervision & 6 months Yoga practice at home (Video assisted)-3rd time point assessments after 6 months of surgery |
10 | Investigations | 1) VBM (Voxel Based Morphometry) (MRI)
2) Neuropsychology Assessment 3) Autonomic Functions Test (HRV) 4) Biochemistry (IL 1 Beta, TNF- α, IL-6, IL-10, Serum Cortisol, BDNF) |
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